Intense positivity in a subset of Islet of Langerhans cells’ cytoplasm.
Ossification: strong positivity in what appear to be osteoblasts.
Is this specific?
Intense cytoplasmic positivity is seen in what appear to be progenitor olfactory interneurons, in the subventricular region ( and the RMS) of the lateral ventricle.
Positivity seen in optic nerve ( punctate) as well as in developing skeletal muscle ( intense)
Upper image of wt mouse shows a tight ALDH1A1 positivity around a capillary.
Lower image of a TASTPM mouse model, using the same antibody, shows a severely disrupted “blood-brain barrier” around a blood vessel.
Almost a mirror image of CD44.
Moderate positivity in epidermal cells. Strong positivity in hair papilla.
Hypodermal muscle cells also appear positive.
Interesting tooth positivity.
Note that what appear to be osteoclasts ( or osteoblasts) are also positive ( see adjacent developing jaw bone.
Mucosal epithelium is also positive ( lower left and upper right of the image).
Strongest positivity is seen in the hair papillae, it seems
Comments on my CD44 positivity are welcomed/appreciated.