Fluorescence seen using TRITC channel.
Note that amyloid is also seen in the capillary walls.
Refer to image of same section but, viewed under TRITC filter using a mercury halide lamp, increased sensitivity is seen
Note the plaques and neurone intracellular positivity ( using Covance SIG-39320) are seen in green.
Microglia ( using Wako 019-19741 ) are clustered around the plaques but, are infrequently seen as amoeboid ( ? activated?)
Note the melanin-containing cells in the dermis?