I was informed that CACNA2D1 ( upper image) and ab2864 ( lower image) targeted two different proteins but, Abcam ‘s alternative names list, for ab2864, includes CACNA2D1.
So, if these two antibodies target the same protein, why do they give very different results? Other images of CACNA2D1/HPA008213 I have uploaded show “excellent” positivity in myelinated nerve fibres.
However, I understand that CACNA2D1 should be present in the superficial laminae of the spinal cord. Abcam’s ab shows this, Atlas’ ab does not.
Comments/elucidation most welcome.