Sequential sections of a TASTPM mouse brain

Upper image of section pretreated with  Formic acid AR.

Lower image of section pretreated using Citric acid HIER.

Note that Formic acid exposes only extracellular plaque amyloid beta.

Citric acid HIER also exposes plaque amyoid but, additionally exposes intracellular amyloid or….is this APP?

Not shown but, in wt mouse brain, I see intracellular neuronal positivity with this ab, only after Citric acid HIER.

Thus this must be APP?