Again, I am not familiar with the distribution pattern of BACE 1 in any tissue.

Comments are welcome.

Frontal cortex

Mouse frontal cortex.

Strong punctate positivity in neuropil; this is more intense on the membranes of many  cells, including the pyramidal cells.

I am not familiar with the distribution pattern of BACE1 in any tissue so upload these images for comments regarding fidelity.

( is this BACE 1 being demonstrated?)

Lateral ventricle region of caudate putamen: a fine, punctate positivity in the neuropil with occasional cell intense cytoplasmic positivity.

Note that the corpus callosum is negative, as are the striae of the Cp.