alpha Synuclein in wt e16 rat: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Developing costal bones ( ribs) Seems to me that osteoblast cytoplasm is positive?
alpha Synuclein in wt rat brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Frontal cortex
alpha Synuclein in wt rat brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Caudate putamen
alpha Synuclein in wt e16 mouse spinal cord: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs
alpha Synuclein in wt mouse brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Hippocampus
alpha Synuclein in wt mouse brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Intense positivity in Glomeruli of GCL. Punctate positivity in neuropil of the ML.
alpha Synuclein in wt mouse brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Caudate putamen: neuropil has a fine punctate positivity. Nerve tracks are negative. NB: plasma in this immersion-fixed specimen is positive as the IgG primary ab is raised in mouse.
alpha Synuclein in TASPM mouse brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Hippocampus
alpha Synuclein in TASPM mouse brain: FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Frontal cortex. Amyloid plaques are negative. There is widespread alpha synuclein positivity in the neuropil which is more intense at the margins of the plaques ( due to compression?).
alpha Synuclein in human brain ( DLB): FFPWS using BD 610787 Image February 13, 2016 Carl Hobbs Lewy bodies are intensely positive.