Dear Histonet,

I searched the archives for references regarding softening nails with 
10% KOH prior to processing and I didn't find anything. I did find that 
there were several people looking for a reference as well, so I thought 
I would share the one I found:

Lewin K, DeWit SA, Lawson R. Softening techniques for nail biopsies. 
Arch Dermatol. 1973 Feb;107(2):223-4.

They had the article in our library, so I have a copy. The authors tried 
many methods of softening and then rated ease of sectioning in a nice 
little table.

Sharron
University of South Florida


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