We are currently using the ER-SP1, PR-SP2, CyclinD1-SP4, & testing the Synaptophysin-SP11.
We did a side by side comparison of these clones of ER/PR and ER-1D5 & PR-636. The rabbit  monoclonals were more sensitive on our series of >200 specimens. It was a small increase in sensitivity. Of course, I don’t know how these would compare on your specimens. We should have an abstract at USCAP2004 on these clones, and probably a paper next year.
The cyclinD1-SP4 is spectacular. Beautiful staining with increased sensitivity over several clones that we have tried.
We are currently testing the Synaptophysin-SP11. So far, it appears to be better than our current clone. We have had some weird artifacts with our current clone that we are not seeing with the SP11. These are very preliminary results.
If there is any other info that you need, please contact me.

Patti Loykasek
PhenoPath Laboratories
Seattle, WA


At the NSH convention in Louisville there was a poster presentation regarding Lab Vision’s new RABBIT monoclonal Ab against Estrogen Receptor (Clone SP1)… has anyone else had any experience with this clone OR their new RABBIT monoclonal Ab against CD3 (Clone SP7) or Cyclin D1/bcl-1 (Clone SP4) or Calretinin (Clone SP13)?



Robert L. Lott, HTL(ASCP)

Manager, Anatomic Pathology

Baptist Health System

800 Montclair Road

Birmingham, AL   35213

205-592-5388  phone

205-592-5646  fax

robert.lott@bhsala.com



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