Blade marks

From:"Bourassa, Patricia" <patricia_bourassa@groton.pfizer.com>

Good afternoon, all!

I'm traditionally a cryostat user, so I'm not used to problems with paraffin
sections.  What causes "blade marks" through the block when you're
sectioning?  For some reason, I'm suddenly getting cuts through my tissue
section.  I've tried fresh blades but it continues to occur.  Any help would
be greatly appreciated!  I know how to trouble shoot a cryo problem, but I'm
a novice when it comes to this!

Patti Bourassa
Pfizer, Groton



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