How this is done depends on what you are wish to examine.
Are you interested in dealing with the epidermis only or with the connective
tissue? Also if dealing with the connective tissue do you also need to
include the hypodermis?

Epidermis and dermis can be separated using EDTA and other techniques and
individual cells prepared using trypsin and oher proteases depending on your
requirments.
If you give us some more details then we may be able to help.
Barry

Edna_J_Gonzalez/Powderject@powderject.com wrote:

> Hello Histonetters:
>
> A co-worker of mine needs to find a physical process or a solution to
> solulize pig skin tissue samples. If you know of a way to solulize skin
> tissue, dissociate cells or how to homogenize skin tissue, please let me
> know. Your help is very appreciated. Thanks.
>
> Edna J. Gonzalez
> PowderJect Vaccines
> Histology Lab.