Louise

S-100 protein are well established as markers of cerebral injury, and have 
been used as markers for CNS glial cell response.

Yamashita N. Ilg EC. Schafer BW. Heizmann CW. Kosaka T. Distribution of a 
specific calcium-binding protein of the S100 protein family, S100A6 
(calcyclin), in subpopulations of neurons and glial cells of the adult rat 
nervous system. Journal of Comparative Neurology. 404:235-57, 1999.

Heizmann CW. from Department of Pediatrics, University of Zurich
published a review, "Ca2+-binding S100 proteins in the central
nervous system", in Neurochemical Research. 24:1097-100, 1999.

These might be a good source for you.

Hiro



----Original Message Follows----
From: Louise Taylor <louiset@mail.saimr.wits.ac.za>
To: histonet <histonet@pathology.swmed.edu>
Subject: anti-rat antibodies
Date: Wed, 01 Mar 2000 12:46:50 +0200


Hi histonetters,

I need some help please. I have been asked to do S100 on rat tissue. I have
no idea where to start looking fo animal primaries, as we generally do
antihuman studies. I would also like some information on what secondary o r
amplification kits would be appropriate. Many thanks

Louise taylor
Research Laboratory
Department of Anatomical Pathology
South African Institute for Medical Research
Johannesburg
South Africa





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